Publications
Selected Recent Publications
Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system.
David M Brinkley, Savannah K Bertolli, Larry A Gallagher, Yongjun Tan, Minola Motha de Silva, Ainsley Brockman, Dapeng Zhang, S. Brook Peterson, Joseph D. Mougous (2025) Pseudomonads coordinate innate defense against viruses and bacteria with a single regulatory system. bioRxiv doi.org/10.1101/2025.02.26.640152
Beyond genomics in Patescibacteria: a trove of unexplored biology packed into ultrasmall bacteria.
Srinivas P, Peterson SB, Gallagher LA, Wang Y, Mougous JD (2024) Beyond genomics in Patescibacteria: a trove of unexplored biology packed into ultrasmall bacteria. PNAS doi: 10.1073/pnas.2419369121
Protein interactions in human pathogens revealed through deep learning
Ian R. Humphreys, Jing Zhang, Minkyung Baek, Yaxi Wang, Aditya Krishnakumar, Jimin Pei, Ivan Anishchenko, Catherine A. Tower, Blake A. Jackson, Thulasi Warrier, Deborah T. Hung, S. Brook Peterson, Joseph D. Mougous, Qian Cong & David Baker (2024) Protein interactions in human pathogens revealed through deep learning. Nature Microbiology doi: 10.1038/s41564-024-01791-x
Streptomyces umbrella toxin particles block hyphal growth of competing species
Qinqin Zhao, Savannah Bertolli, Young-Jun Park, Yongjun Tan, Kevin J. Cutler, Pooja Srinivas, Kyle L. Asfahl, Citlali F. Garcia, Larry A. Gallagher, Yaqiao Li, Yaxi Wang, Devin Coleman-Derr, Frank DiMaio, Dapeng Zhang, S. Brook Peterson, David Veesler & Joseph D. Mougous (2024) Streptomyces umbrella toxin particles block hyphal growth of competing species. Nature doi: 10.1038/s41586-024-07298-z
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
Wang Y, Gallagher LA, Andrade PA, Liu A, Humphreys IR, Turkarslan S, Cutler KJ, Arrieta-Ortiz ML, Li Y, Radey MC, Cong Q, Baker D, Baliga NS, Peterson SB, Mougous JD (2023) Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle. Cell doi: 10.1016/j.cell.2023.08.017.
Omnipose: a high-precision, morphology-independent solution for bacterial cell segmentation
Cutler KJ, Stringer C, Lo TW, Rappez L, Stroustrup N, Peterson SB, Wiggins PA, Mougous JD (2022) Omnipose: a high-precision, morphology-independent solution for bacterial cell segmentation. Nature Methods doi: 10.1038/s41592-022-01639-4.